Cancerous breast tissue shows elevated bacteria levels, new research shows

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By comparing breast cancer tissue with healthy breast tissue, Cleveland Clinic researchers found there was an imbalance of bacteria.

The same goes for Lisa Moeller; no family history and no so-called breast cancer genes, known as BRCA 1 or 2.

The total known number of mutations that can lead to breast cancer is now 180. "Women are very strong".

Yet breast cancer is still one of the most deadly forms of cancer for many women in the U.S., coming second only to lung cancer for some demographic groups.

"Scientists are not in competition against each other", said professor Peter Kraft of Harvard T.H. Chan School of Public Health. Complete results of the study can be found in the journal OncoTarget. "That is when it is curable and we have more treatment options if found early", McCain said.

While 41 percent of those receiving conventional treatment for lung cancer survive for at least five years, only 20 percent of those opting for alternative medicines do so, the research adds. Your weight, activity level, alcohol consumption and breast density may determine your risk of breast cancer.

Inheriting either of these genes raises the lifetime risk of developing the disease by as much as 90 per cent for BRCA1 and 85 per cent for BRCA2.

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The combined effect of these variants is likely to be "considerable" said the researchers.

The study uncovered 65 genetic variants that predispose women to the overall risk of the disease and seven variants that predispose women to oestrogen-receptor negative breast cancer, which does not respond to tamoxifen, a treatment used to reduce the risk of breast cancer.

Read the full ER-negative study in Nature Genetics. However, we have developed a mathematical algorithm that incorporates the effect of each of the variations worn by a woman and which calculates from this the probability of her developing breast cancer, " says Simard, who sees in this new tool a way to identify women without a family history of breast cancer or ovarian cancer, but who are at high risk of suffering from such a cancer.

'These women may benefit from more intensive screening, starting at a younger age, or using more sensitive screening techniques, allowing early detection and prevention of the disease'.

"If you could stop that (cancer) from ever happening to you that would change my quality of life and it would have meant I could have had a second child".

"But there are other risk factors".

The newly identified risk regions almost double the number that are already known, thereby bringing the number of known common variants associated with breast cancer to around 180.

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